Pesquisa | BVS Violência e Saúde

1.

Deciphering breast cancer: from biology to the clinic.

Nolan, Emma; Lindeman, Geoffrey J; Visvader, Jane E.

Cell ; 186(8): 1708-1728, 2023 04 13.

Artigo em Inglês | MEDLINE | ID: mdl-36931265

2.

Archival single-cell genomics reveals persistent subclones during DCIS progression.

Wang, Kaile; Kumar, Tapsi; Wang, Junke; Minussi, Darlan Conterno; Sei, Emi; Li, Jianzhuo; Tran, Tuan M; Thennavan, Aatish; Hu, Min; Casasent, Anna K; Xiao, Zhenna; Bai, Shanshan; Yang, Lei; King, Lorraine M; Shah, Vandna; Kristel, Petra; van der Borden, Carolien L; Marks, Jeffrey R; Zhao, Yuehui; Zurita, Amado J; Aparicio, Ana; Chapin, Brian; Ye, Jie; Zhang, Jianjun; Gibbons, Don L; Sawyer, Ellinor; Thompson, Alastair M; Futreal, Andrew; Hwang, E Shelley; Wesseling, Jelle; Lips, Esther H; Navin, Nicholas E.

Cell ; 186(18): 3968-3982.e15, 2023 08 31.

Artigo em Inglês | MEDLINE | ID: mdl-37586362

3.

Bacteria in tumors "hit the road" together.

Longmore, Gregory D.

Cell ; 185(8): 1292-1294, 2022 04 14.

Artigo em Inglês | MEDLINE | ID: mdl-35427497

4.

Tissue-resident FOLR2⁺ macrophages associate with CD8⁺ T cell infiltration in human breast cancer.

Nalio Ramos, Rodrigo; Missolo-Koussou, Yoann; Gerber-Ferder, Yohan; Bromley, Christian P; Bugatti, Mattia; Núñez, Nicolas Gonzalo; Tosello Boari, Jimena; Richer, Wilfrid; Menger, Laurie; Denizeau, Jordan; Sedlik, Christine; Caudana, Pamela; Kotsias, Fiorella; Niborski, Leticia L; Viel, Sophie; Bohec, Mylène; Lameiras, Sonia; Baulande, Sylvain; Lesage, Laëtitia; Nicolas, André; Meseure, Didier; Vincent-Salomon, Anne; Reyal, Fabien; Dutertre, Charles-Antoine; Ginhoux, Florent; Vimeux, Lene; Donnadieu, Emmanuel; Buttard, Bénédicte; Galon, Jérôme; Zelenay, Santiago; Vermi, William; Guermonprez, Pierre; Piaggio, Eliane; Helft, Julie.

Cell ; 185(7): 1189-1207.e25, 2022 03 31.

Artigo em Inglês | MEDLINE | ID: mdl-35325594

5.

Tumor-resident intracellular microbiota promotes metastatic colonization in breast cancer.

Fu, Aikun; Yao, Bingqing; Dong, Tingting; Chen, Yongyi; Yao, Jia; Liu, Yu; Li, Hang; Bai, Huiru; Liu, Xiaoqin; Zhang, Yue; Wang, Chunhui; Guo, Yajing; Li, Nan; Cai, Shang.

Cell ; 185(8): 1356-1372.e26, 2022 04 14.

Artigo em Inglês | MEDLINE | ID: mdl-35395179

6.

XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation.

Richart, Laia; Picod-Chedotel, Mary-Loup; Wassef, Michel; Macario, Manon; Aflaki, Setareh; Salvador, Marion A; Héry, Tiphaine; Dauphin, Aurélien; Wicinski, Julien; Chevrier, Véronique; Pastor, Sonia; Guittard, Geoffrey; Le Cam, Samuel; Kamhawi, Hanya; Castellano, Rémy; Guasch, Géraldine; Charafe-Jauffret, Emmanuelle; Heard, Edith; Margueron, Raphaël; Ginestier, Christophe.

Cell ; 185(12): 2164-2183.e25, 2022 06 09.

Artigo em Inglês | MEDLINE | ID: mdl-35597241

7.

Transition to invasive breast cancer is associated with progressive changes in the structure and composition of tumor stroma.

Risom, Tyler; Glass, David R; Averbukh, Inna; Liu, Candace C; Baranski, Alex; Kagel, Adam; McCaffrey, Erin F; Greenwald, Noah F; Rivero-Gutiérrez, Belén; Strand, Siri H; Varma, Sushama; Kong, Alex; Keren, Leeat; Srivastava, Sucheta; Zhu, Chunfang; Khair, Zumana; Veis, Deborah J; Deschryver, Katherine; Vennam, Sujay; Maley, Carlo; Hwang, E Shelley; Marks, Jeffrey R; Bendall, Sean C; Colditz, Graham A; West, Robert B; Angelo, Michael.

Cell ; 185(2): 299-310.e18, 2022 01 20.

Artigo em Inglês | MEDLINE | ID: mdl-35063072

8.

Estrogen receptor gets a grip on RNA.

Katzenellenbogen, Benita S.

Cell ; 184(20): 5086-5088, 2021 09 30.

Artigo em Inglês | MEDLINE | ID: mdl-34559987

9.

Transforming lives through genetics.

Cell ; 184(8): 1953-1955, 2021 04 15.

Artigo em Inglês | MEDLINE | ID: mdl-33831377

10.

Compromised nuclear envelope integrity drives TREX1-dependent DNA damage and tumor cell invasion.

Nader, Guilherme Pedreira de Freitas; Agüera-Gonzalez, Sonia; Routet, Fiona; Gratia, Matthieu; Maurin, Mathieu; Cancila, Valeria; Cadart, Clotilde; Palamidessi, Andrea; Ramos, Rodrigo Nalio; San Roman, Mabel; Gentili, Matteo; Yamada, Ayako; Williart, Alice; Lodillinsky, Catalina; Lagoutte, Emilie; Villard, Catherine; Viovy, Jean-Louis; Tripodo, Claudio; Galon, Jérôme; Scita, Giorgio; Manel, Nicolas; Chavrier, Philippe; Piel, Matthieu.

Cell ; 184(20): 5230-5246.e22, 2021 09 30.

Artigo em Inglês | MEDLINE | ID: mdl-34551315

11.

The bone microenvironment invigorates metastatic seeds for further dissemination.

Zhang, Weijie; Bado, Igor L; Hu, Jingyuan; Wan, Ying-Wooi; Wu, Ling; Wang, Hai; Gao, Yang; Jeong, Hyun-Hwan; Xu, Zhan; Hao, Xiaoxin; Lege, Bree M; Al-Ouran, Rami; Li, Lucian; Li, Jiasong; Yu, Liqun; Singh, Swarnima; Lo, Hin Ching; Niu, Muchun; Liu, Jun; Jiang, Weiyu; Li, Yi; Wong, Stephen T C; Cheng, Chonghui; Liu, Zhandong; Zhang, Xiang H-F.

Cell ; 184(9): 2471-2486.e20, 2021 04 29.

Artigo em Inglês | MEDLINE | ID: mdl-33878291

12.

ERα is an RNA-binding protein sustaining tumor cell survival and drug resistance.

Xu, Yichen; Huangyang, Peiwei; Wang, Ying; Xue, Lingru; Devericks, Emily; Nguyen, Hao G; Yu, Xiuyan; Oses-Prieto, Juan A; Burlingame, Alma L; Miglani, Sohit; Goodarzi, Hani; Ruggero, Davide.

Cell ; 184(20): 5215-5229.e17, 2021 09 30.

Artigo em Inglês | MEDLINE | ID: mdl-34559986

13.

G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.

Prentzell, Mirja Tamara; Rehbein, Ulrike; Cadena Sandoval, Marti; De Meulemeester, Ann-Sofie; Baumeister, Ralf; Brohée, Laura; Berdel, Bianca; Bockwoldt, Mathias; Carroll, Bernadette; Chowdhury, Suvagata Roy; von Deimling, Andreas; Demetriades, Constantinos; Figlia, Gianluca; de Araujo, Mariana Eca Guimaraes; Heberle, Alexander M; Heiland, Ines; Holzwarth, Birgit; Huber, Lukas A; Jaworski, Jacek; Kedra, Magdalena; Kern, Katharina; Kopach, Andrii; Korolchuk, Viktor I; van 't Land-Kuper, Ineke; Macias, Matylda; Nellist, Mark; Palm, Wilhelm; Pusch, Stefan; Ramos Pittol, Jose Miguel; Reil, Michèle; Reintjes, Anja; Reuter, Friederike; Sampson, Julian R; Scheldeman, Chloë; Siekierska, Aleksandra; Stefan, Eduard; Teleman, Aurelio A; Thomas, Laura E; Torres-Quesada, Omar; Trump, Saskia; West, Hannah D; de Witte, Peter; Woltering, Sandra; Yordanov, Teodor E; Zmorzynska, Justyna; Opitz, Christiane A; Thedieck, Kathrin.

Cell ; 184(3): 655-674.e27, 2021 02 04.

Artigo em Inglês | MEDLINE | ID: mdl-33497611

14.

Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy.

Krug, Karsten; Jaehnig, Eric J; Satpathy, Shankha; Blumenberg, Lili; Karpova, Alla; Anurag, Meenakshi; Miles, George; Mertins, Philipp; Geffen, Yifat; Tang, Lauren C; Heiman, David I; Cao, Song; Maruvka, Yosef E; Lei, Jonathan T; Huang, Chen; Kothadia, Ramani B; Colaprico, Antonio; Birger, Chet; Wang, Jarey; Dou, Yongchao; Wen, Bo; Shi, Zhiao; Liao, Yuxing; Wiznerowicz, Maciej; Wyczalkowski, Matthew A; Chen, Xi Steven; Kennedy, Jacob J; Paulovich, Amanda G; Thiagarajan, Mathangi; Kinsinger, Christopher R; Hiltke, Tara; Boja, Emily S; Mesri, Mehdi; Robles, Ana I; Rodriguez, Henry; Westbrook, Thomas F; Ding, Li; Getz, Gad; Clauser, Karl R; Fenyö, David; Ruggles, Kelly V; Zhang, Bing; Mani, D R; Carr, Steven A; Ellis, Matthew J; Gillette, Michael A.

Cell ; 183(5): 1436-1456.e31, 2020 11 25.

Artigo em Inglês | MEDLINE | ID: mdl-33212010

15.

Direct Tumor Killing and Immunotherapy through Anti-SerpinB9 Therapy.

Jiang, Liwei; Wang, Yi-Jun; Zhao, Jing; Uehara, Mayuko; Hou, Qingming; Kasinath, Vivek; Ichimura, Takaharu; Banouni, Naima; Dai, Li; Li, Xiaofei; Greiner, Dale L; Shultz, Leonard D; Zhang, Xiaolong; Sun, Zhen-Yu Jim; Curtin, Ian; Vangos, Nicholas E; Yeoh, Zoe C; Geffken, Ezekiel A; Seo, Hyuk-Soo; Liu, Ze-Xian; Heffron, Gregory J; Shah, Khalid; Dhe-Paganon, Sirano; Abdi, Reza.

Cell ; 183(5): 1219-1233.e18, 2020 11 25.

Artigo em Inglês | MEDLINE | ID: mdl-33242418

16.

Regulation of Collective Metastasis by Nanolumenal Signaling.

Wrenn, Emma D; Yamamoto, Ami; Moore, Breanna M; Huang, Yin; McBirney, Margaux; Thomas, Aaron J; Greenwood, Erin; Rabena, Yuri F; Rahbar, Habib; Partridge, Savannah C; Cheung, Kevin J.

Cell ; 183(2): 395-410.e19, 2020 10 15.

Artigo em Inglês | MEDLINE | ID: mdl-33007268

17.

Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity.

Lu, Yiwen; Zhao, Qiyi; Liao, Jian-You; Song, Erwei; Xia, Qidong; Pan, Jiayao; Li, Yihong; Li, Jiaqian; Zhou, Boxuan; Ye, Yingying; Di, Can; Yu, Shubin; Zeng, Yunjie; Su, Shicheng.

Cell ; 180(6): 1081-1097.e24, 2020 03 19.

Artigo em Inglês | MEDLINE | ID: mdl-32142650

18.

The BRCA Tumor Suppressor Network in Chromosome Damage Repair by Homologous Recombination.

Zhao, Weixing; Wiese, Claudia; Kwon, Youngho; Hromas, Robert; Sung, Patrick.

Annu Rev Biochem ; 88: 221-245, 2019 06 20.

Artigo em Inglês | MEDLINE | ID: mdl-30917004

19.

Cytotoxic innate lymphoid cells sense cancer cell-expressed interleukin-15 to suppress human and murine malignancies.

Kansler, Emily R; Dadi, Saïda; Krishna, Chirag; Nixon, Briana G; Stamatiades, Efstathios G; Liu, Ming; Kuo, Fengshen; Zhang, Jing; Zhang, Xian; Capistrano, Kristelle; Blum, Kyle A; Weiss, Kate; Kedl, Ross M; Cui, Guangwei; Ikuta, Koichi; Chan, Timothy A; Leslie, Christina S; Hakimi, A Ari; Li, Ming O.

Nat Immunol ; 23(6): 904-915, 2022 06.

Artigo em Inglês | MEDLINE | ID: mdl-35618834

20.

Type I IFNs promote cancer cell stemness by triggering the epigenetic regulator KDM1B.

Musella, Martina; Guarracino, Andrea; Manduca, Nicoletta; Galassi, Claudia; Ruggiero, Eliana; Potenza, Alessia; Maccafeo, Ester; Manic, Gwenola; Mattiello, Luca; Soliman Abdel Rehim, Sara; Signore, Michele; Pietrosanto, Marco; Helmer-Citterich, Manuela; Pallocca, Matteo; Fanciulli, Maurizio; Bruno, Tiziana; De Nicola, Francesca; Corleone, Giacomo; Di Benedetto, Anna; Ercolani, Cristiana; Pescarmona, Edoardo; Pizzuti, Laura; Guidi, Francesco; Sperati, Francesca; Vitale, Sara; Macchia, Daniele; Spada, Massimo; Schiavoni, Giovanna; Mattei, Fabrizio; De Ninno, Adele; Businaro, Luca; Lucarini, Valeria; Bracci, Laura; Aricò, Eleonora; Ziccheddu, Giovanna; Facchiano, Francesco; Rossi, Stefania; Sanchez, Massimo; Boe, Alessandra; Biffoni, Mauro; De Maria, Ruggero; Vitale, Ilio; Sistigu, Antonella.

Nat Immunol ; 23(9): 1379-1392, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-36002648

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